Thursday, June 20
12:30 Registration
13:30 Opening
13:40 What we've achieved and what are we dreaming about?
14:45 Break
15:15 A Glimpse into the future
16:15 Break
16:45 NLHI fellowships competition
17:30 Wiek van Gilst Collaboration Award
18:00 Wrap-up
18:05 Walking network dinner
19:00 Ceremony Wiek van Gilst Collaboration Award
21:00 End of Day 1

Friday, June 21
8:00 Registration with coffee & tea
8:30 Opening
8:40 Keynote - DCVA
9:10 Einthoven dissertation competition
09:45 Change rooms
9:55 PARALLEL SESSIONS #1
10:55 Break
11:15 PARALLEL ESSION #2
12:30 LUNCH
13:30 PARALLEL SESSION #3
14:30 Change rooms
14:40 PARALLEL SESSION #4
15:55 Coffee break
16:15 Closing session
Awarding sessions: national and international fellowships prize, poster prize & Einthoven prize.
17:00 END & drinks

Registration is still open for the 8th DCVA-NLHI Translational Cardiovascular Research Meeting.
Reserve your spot HERE - space is limited!

Are you ready to showcase your cutting-edge research at the 8th Translational Cardiovascular Research Meeting on June 20-21?

Don’t miss this chance! The deadline for abstract submission is approaching fast—June 14th! We're accepting a maximum of 35 posters, so get your submissions in early.
From these, 10 exceptional candidates will be selected to present during the moderated poster session on June 21st. Top 3 poster presentations will be awarded prizes of €300, €200, and €100. 💰

We can't wait to see your innovative work! Submit your poster here: https://lnkd.in/eRq8G5Nz
Remember, it's first come, first served—the call will close after 35 submissions.

Every year, the Netherlands Heart Institute awards fellowships to young scientists, allowing them to work abroad for up to a year. This fellowship program is supported by the Foundation Friends of Cardiology (Vrienden van de Cardiologie).

During the 8th Translational Cardiovascular Research Meeting of the DCVA and the Netherlands Heart Institute, three applicants will be invited to present their proposals. The awarding session will take place during the closing session on Friday, June 21, 2024.

Registrations for the proposals are now closed. The three finalists from this year's fellowship submissions are Yvemarie Somsen, Rick Volleberg, Myrthe van der Heide. Congratulations on your outstanding proposals! 🏆🏅🥇

Initiated by the Dutch Society of Cardiology (Nederlandse Vereniging voor Cardiologie (NVVC)) and Netherlands Heart Institute, the Einthoven Dissertation Awards recognize outstanding cardiovascular dissertations.
A total of €6,000 will be awarded:

1st Prize: €3,000
2nd Prize: €2,000
3rd Prize: €1,000

We are excited to announce the top 3 submissions for this year's Einthoven Dissertation Award. Congratulations to:

🔸Marie-Sophie de Koning - Thiol-based cardioprotection
🔸Alexander van Rosendael, MD PhD - The role of Detailed Coronary Atherosclerosis Evaluation by CT in Ischemic Heart Disease
🔸Arja Suzanne Vink - Diagnostics and modulators in long QT syndrome towards a better assesment in the young

The candidates will present their thesis on Friday the 21nd (9:10-9:40). The awarding session takes place at 16:15-17:00.

DCVA Workshop: How to form a consortium?
Chairs: Rebecca Abma Schouten (Hartstichting), Prof. Dr. Hester den Ruijter (UMCU).

Do you have a big idea for a cardiovascular research collaboration? Or would you like to contribute to a consortium? How to approach this? The DCVA and funders like the Dutch Heart Foundation like to meet you. Who does what in the process of forming a consortium? What steps are taken, and which decisions are made? What tips and tricks could we learn from experienced consortium leaders? Come and join us in this high-profile session, in which your new consortium might be conceived.

Heart failure: Mechanism and treatment
Chairs: Prof. Dr. Louise Bowman (University of Oxford), Prof. Dr. Peter van der Meer (UMCG).

1. Dilated Cardiomyopathies: from Genes to Inflammation - Stephane Heymans, Maastricht University, Double Dosis CVON project.

2. Incident HFpEF and time-dependent changes in markers of LVDD severity in women and men at high cardiovascular risk - Anne-Mar van Ommen, UMC Utrecht, RECONNEXT consortium.

3. A novel concept of Sodium reduction in chronic heart failure: a randomized clinical pilot study - Roland van Kimmenade, RadboudUMC.

4. Long-term Outcomes of DCD Heart Transplantation - Selma Kaffka genaamd Dengler, UMC Utrecht.

Digital Health: better use of the data
Chairs: Prof. Dr. Folkert Asselbergs.

1. CARRIER - From ''Big Data'' to optimizing cardiovascular risk management - Rutger van Mierlo, Maastricht University, CARRIER.

2. Video monitoring of heart and respiration rate in the ICU: a validation study - Rik van Esch, Technische Universiteit Eindhoven.

3. Distinction between Ischemic Stroke and Transient Ischemic Attack based on Admission Non-contrast Computed Tomography using Deep Learning Model - Hyunho Mo, Erasmus MC.

4. Effect of home monitoring on blood pressure and weight in primary care patients with a high risk of cardiovascular disease: a 12-month matched cohort study - Eline Meijer, LUMC.

Innovation in brain protection
Chairs: Prof. Dr. Wouter Jukema (LUMC), Prof. Dr. Geert Jan Biessels (UMCU).

1. Intracranial Arteriosclerosis: a major risk factor for stroke? - Daniël Bos, ErasmusMC, DCVA, ICAS.

2. The Dutch Intracerebral haemorrhage Surgery Trial (DIST): minimally invasive endoscopy-guided surgery in patients with spontaneous, supratentorial intracerebral haemorrhage - Ruben Dammers, Erasmus MC, CONTRAST consortium; Dutch Heart Foundation.

3. Hypertension, Intracranial arteriosclerosis, and Structural Brain Changesin patients with TIA or ischemic stroke - Xi Li, ErasmusMC.

4. Rationale and design of the CASES trial. Direct stenting of carotid stenosis/occlusion during endovascular thrombectomy - Maarten Uyttenboogaart, UMCG, Contrast.

Aortic and pulmonary artery disease: new insights
Chairs: Prof. Dr. Wolfgang Koenig (German Heart Centre of Munich), Dr. Kak Khee Yeung (Amsterdam UMC).

1. Increased vascular smooth muscle cell senescence in aneurysmal disease - Ingrid van der Pluijm, Cardiovascular Institute Erasmus MC.

2. BMP9 attenuates IL-33 signaling and prevents endothelial-to-mesenchymal transition in a model of Pulmonary Arterial Hypertension - Clarissa Becher, LUMC, PHAEDRA Impact consortium.

3. Computational modelling of pulmonary arterial hypertension - Sander Schomaker, University of Groningen.

4. A Novel Tool for Early Detection and Therapeutic Screening Targeting TGF-β Signaling in Pulmonary Arterial Hypertension - Marius Wits, LUMC, PHAEDRA-IMPACT.

Atherosclerosis: non invasive treatment and inflammation reduction
Chairs: Prof. Dr. Gerard Pasterkamp (UMC Utrecht), Prof. Dr. Menno de Winther
(Amsterdam UMC).

1. Effect of low-dose colchicine on pericoronary inflammation and coronary plaque composition in chronic coronary disease - Aernoud Fiolet, UMCU.|

2. Aging promotes mast cell activation and antigen presenting capacity in atherosclerosis - Marie Depuydt, LACDR, Leiden University, CVON, GENIUS II.

3. First-in-human use of DMUA/HIFU therapy for the treatment of atherosclerotic plaques in the femoral artery: a safety and feasibility study - Robbert Wiggers, UMC Utrecht.

4. Antigenic peptides for atherosclerosis protection - Jill de Mol, LACDR, Leiden University.

5. Resident and virus specific CD8 T-cells in atherosclerosis - Bram Slütter, LACDR, Leiden University.

Clinical aspects of atrial fibrillation
Chairs: Prof. Dr. Isabelle van Gelder (UMCG), Prof. Dr. Otto Smiseth (Oslo University Hospital)

1. Personalized identification and quantification of electropathology by high-resolution epicardial mapping - Natasja de Groot, ErasmusMC.

2. A Novel High-Density Sequential Mapping Strategy for Atrial Fibrillation: Optimizing Ablation Target Localization - Ozan Özgul, Maastricht University.

3. Atrial cardiomyopathy in patients with paroxysmal AF – data from RACE V - Martijn van de Lande, Groningen University.

4. Early and Late Lesion Visualization with Cardiac Magnetic Resonance After Atrial Fibrillation Ablation - Sophie Rier, Haga Teaching Hospital.

5. Atrial remodeling is associated with increased POAF burden and worse outcome post cardiac surgery - RACE V Tissue Bank / Circadian occurrence patterns of atrial fibrillation after cardiac surgery. during 2.5 years of continuous rhythm monitoring - Michal Kawczynski, Maastricht University.

Energetic and metabolic aspects of cardiovascular disease
Chairs: Prof. Dr. Pieter Doevendans (UMCU), Prof. Dr. Steven Chamuleau (Amsterdam UMC)

1. GLP 1 and Heartfailure - Prof. Dr. Peter van der Meer (UMCG).

2. Impaired cardiac mitochondrial bioenergetics contributes to loss of cardiac function, in a porcine multiple risk factor model - Lotte Maria Zandbergen, Erasmus MC, Reconnext consortium.

3. Proteomics and Metabolomics for Biomarker Discovery in Abdominal Aortic Aneurysm and Post-EVAR Sac Volume - Isabella Kardys, Erasmus MC.

4. Meta-analysis of RNAseq Data from Two Large Atrial Tissue Banks Identifies More than 8000 Transcripts Associated with AF and Suggests Prominent Roles for Mitochondrial Processes, Energy Metabolism, and Cell Signaling: the CATCH ME and RACE V Consortia - Aaron Isaacs, CARIM, Maastricht University.

5. GLP 1 and artherosclerose - Fabrice Martens (Amsterdam UMC).

Linking heart failure and arrhythmias
Chairs: Dr. Saskia Beeres (LUMC), Prof. Dr. Ajay Shah, (King’s college London).

1. Cytotoxic T-Cells Drive Cardiac Inflammation in Dilated Cardiomyopathy - Maurits Sikking, MUMC, Double Dose.

2. First experience with a novel mapping system for MRI-guided electrophysiological procedures - Giulia de Zan, UMC Utrecht.

3. Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience - Sean Jurgens, Amsterdam AMC, PREDICT2, Dekker beurs Junior Clinical Scientist.

4. Unravelling the role of autonomic nervous system dysfunction in inherited arrhythmia syndromes - Molly O’Reilly, Amsterdam UMC.

Regeneration, the only route to cardiac repair
Chairs: Dr. Linda van Laake (UMC Utrecht), Prof. Dr. Marie-José Goumans (LUMC) Prof. Dr. Jolanda van der Velden (Amsterdam UMC).

1. Unraveling the significance of the epicardium in cardiac repair mechanisms - Anke Smits, LUMC.

2. AAV-mediated gene therapy strategy impacts cardiac function in “humanized PLN-R14del mice”: a preclinical model of PLN-R14del induced cardiomyopathy - Karen Gaar-Humphreys, UMC Utrecht.

3. The effect of extracellular matrix treatment on cardiac function and tissue homeostasis post myocardial infarction: a systematic review of preclinical studies - Atze van der Pol, Eindhoven University.

4. The Creation of a Cardiac Bioreactor - Ex Situ Heart Perfusion for Therapeutic Purposes - Mats Vervoorn, UMC Utrecht.

Innovation in atrial fibrillation detection and treatment
Chairs: Dr. Peter Loh (UMC Utrecht), Dr. Hadrian Wijnmaalen (LUMC).

1. Clinical, histological and gene expression profile of atrial cardiomyopathy - Joris Winters, Maastricht University.

2. Screening and detection of atrial fibrillation in general practice - Ralf Harskamp, Amsterdam UMC.

3. Atrial fibrillation: sex differences in epidemiology, risk factors, and prognosis - Maryam Kavousi, Erasmus MC.

4. Preprocedural atrial fibrillation burden is associated with recurrence in patients undergoing atrial fibrillation ablation: Findings from the ISOLATION AF Ablation Cohort Study - Zarina Habibi, Maastricht University.

Registries: good data in…
Chairs: Dennis van Veghel (NHR, UMCG).

1. The national cardiomyopathy registry; the start of something great - Peter-Paul Zwetsloot, Netherlands Heart Institute, CARMA project, DOUBLE-DOSE.

2. Health Information- and Healthcare Seeking Behaviour among Ethnically and Socioeconomically Diverse Women and Men with Ischemic Heart Disease in the Netherlands: A Qualitative Study - Bryn Hummel, Amsterdam UMC.

3. A Comprehensive Analysis of Women's Participation in Cardiovascular Trials - Marte van der Bijl, ErasmusMC, Marie Curie project (Hartstichting), embedded in the IMPRESS consortium.

4. Coupling NHR-DHD for complex interventions - Maaike Roefs, Nederlandse Hart Registratie, Heart4Data.

Workshop AI-ECG 13:30 - 15:30 (NB: during Block #3 & #4)
Analysis/Interpretation of the Electrocardiogram by using Artificial Intelligence Techniques

1. AI applications in clinical electrocardiography: from ideas to reality - Cees A. Swenne, Ph.D. Cardiology Department, LUMC.

2. Artificial intelligence: definitions, basic approaches, validation procedures - Agnese Sbrollini, Ph.D. Marche Polytechnic University, Ancona, Italy.

3. Overview of recent AI-ECG studies in the University Medical Center Utrecht - (online from the U.S.A.) Rutger R. van de Leur, M.D. Heart & Lungs Division, UMC Utrecht.

Note: Due to the intimate character of this workshop, limited spots are available! You will be notified when the workshop is full.

Developments in CHD
Chairs: Prof. Dr. Monique Jongboed (LUMC), Dr. Beatrijs Bartelds (Erasmus MC).

1. The clinical potential and mechanistic promise of SGLT2i in adult congenital heart disease-related heart failure - Anastasia D. Egorova, LUMC, NHI working group ACHD-related HF.

2. Transposition of the Great Arteries; a cell lineage study in mice - Tamara Borsboon, LUMC, OUTREACH.

3. 30 years’ experience in percutaneous pulmonary artery interventions in patients with transposition of the great arteries after the arterial switch operation - Renée Joosen, UMC Utrecht, OUTREACH.

4. Ventriculo-arterial coupling in pulmonary regurgitation after transannular patch repair of right ventricular outflow tract obstruction - Rahi Alipour Symakani, Erasmus MC, OUTREACH.

5. Toward Living Homografts: Immunomodulation of Pediatric Heart Valves - Marijn Peters, Eindhoven University, Zwaartekracht and OUTREACH.

Stem cells and disease modeling
Chairs: prof. dr. Eva van Rooij (UMCU), prof. dr. Robert Passier (LUMC).

1. Increased oxidative stress alters coronary microvascular tone in exercising swine with multiple comorbidities - Ruben van Drie, Erasmus MC.

2. In vitro Disease Modelling of Amyloid Cardiomyopathy - Jiabin Qin, UMC Utrecht.

3. Stage-specific effects of Insulin and Wnt on cell fate decisions in human induced pluripotent stem cell-derived cardiomyocytes - Jan Willem Buikema, Amsterdam UMC, Young@Heart.

4. Generation of isogenic allelic series of LMNA-mutated hiPSC lines using the STRAIGHT-IN platform - Viviana Meraviglia, LUMC.

5. Cardiotoxicity Challenges Meet Stem Cell Solutions: A Cutting-edge Approach - Verena Schwach, University of Twente.

Early detection and outcome prediction
Chairs: Prof. Dr. Aad van der Lugt (Erasmus MC).

1. Perfusion DSA - Separating successful reperfusion during endovascular treatment - Matthijs van der Sluijs, Erasmus MC, Accurate/Q-Maestro.

2. The CROSSROADS-study - Inger de Ridder, Maastricht UMC.

3. A decision-analytic model to evaluate cost-effectiveness of regional implementation of a mobile stroke unit - Peter van Hulst, Erasmus MC, ICAI Stroke lab.

4. Prehospital triage of patients with a suspected acute stroke (PRESTO-2): development, implementation and evaluation of a decision support tool - Ruben van de Wijdeven, Erasmus MC, CONTRAST, Dekkerbeurs.

5. The importance of a fine-grained long-term follow-up of acute stroke interventions - Sarah Zandvliet, Erasmus MC, RadboudUMC, CONTRAST.

Machine learning and AI
Chairs: Dr. Ir. Joost Lumens (MUMC) Nico Bruining (Erasmus MC).

1. Predicting abnormal echocardiograms using deep learning applied to the 12-lead electrocardiogram - Bauke Arends, UMC Utrecht.

2. AI-Driven ECG Analysis for Characterization of Atrial Fibrillation during Sinus Rhythm - Ozan Özgül, Maastricht University.

3. How To Turn Big Data Into Cardiovascular Insights - Concrete Opportunities and Obstacles - Malin Overmars, UMC Utrecht.

4. Early detection of Atrial fibrillation in ICU using Meta-learning - Mehran Moazeni, UMC Utrecht.

5. Using human genetics to inform and prioritise drug development - Amand Floriaan Schmidt, Amsterdam UMC.