Each week, three hundred people in The Netherlands have a sudden cardiac arrest outside of a hospital. Survival is very poor. The DCVA invests in research that could lead to prediction and prevention of sudden cardiac arrest.
How to predict the unpredictable
The Predicting sudden cardiac arrest 2 or PREDICT2 is the sequel to PREDICT1, and aims to predict the unpredictable by identifying genetic and non-genetic factors that lead to sudden cardiac death, and by using these factors for the development of risk prediction algorithms. Also it will conduct clinical studies for risk assessment and identify mechanisms underlying sudden cardiac death to develop new therapeutic strategies.
Sudden cardiac arrest continues to be a major public health problem, representing almost 20% of all deaths in industrialized societies. It accounts for ~50% of all heart disease deaths, an important subset of which consists of individuals not previously diagnosed with heart disease. If sudden cardiac arrest could be predicted, measures could be taken to prevent this acute and deadly event.