The main research interests of the group of Van der Velden is to define cellular dysfunction in inherited cardiomyopathies, and identify pathomechanisms which may be target for drug interventions. Their research involves functional studies in single cardiomyocytes and multicellular tissue preparations in cardiac samples from animal models, human cardiac tissue, and stem cell-derived models. These laboratory studies are combined with state-of-the-art imaging of the heart of patients in close collaboration with the department of Clinical Genetics, Cardiology and Nuclear Medicine.
